What if you reconciled with your acne-prone skin?

Freeing yourself from acne: this is a mission we take very seriously, and Cleanance skincare products continue to demonstrate our commitment for 30 years to all acne-prone skin.

Purify, correct, accompany or beautify oily or acne-prone skin of adolescents or adult women: a complete range that guarantees efficacy and high tolerance, alone or in combination with drug treatment. Don't give up, Cleanance is your best ally in this fight!

Cleanance A.H.A Exfoliating Serum

The dermatological innovation to take control of your skin as of now. Because imperfections affect nearly one out of two women today, discover the Cleanance anti-imperfections serum. The 1st ultra-concentrated serum, composed of a duo of dermatological acids 1.5 times more efficient than salicylic acid*. Its exclusive formula of only 10 ingredients tightens your pores and reduces marks and blemishes. 

A minimalist, effective and ultra-concentrated formula 

This is not a magic formula, just an ultra-concentrated, ultra-effective dermatological acid formula. 


With only 10 ingredients, 99% of which are of natural origin, it is the 1st serum with an efficient patented* duo of dermatological acids, offering 1.5 times the effectiveness of salicylic acid.**  

  • Lactic acid (2.7%) reduces excess keratin and dead cells that accumulate on the skin's surface thanks to its keratolytic effect. 
  • Succinic acid (3%) unclogs pores and regulates the development of keratinocytes - cells that constitute the essential part of the epidermis. 
  • Glutamic acid, in complement of the duo of lactic and succinic acids, regulates the production of sebum in a lasting way, by fighting against the excess of sebum favourable with the proliferation of bacterium (microbiome dysbiosys) responsible for the imperfections. 


To eliminate shine and imperfections of sensitive oily or acne-prone skin

Cleanance Comedomed: 

The anti-imperfections concentrate to (finally) 

get rid of pimples. 

A unique process: an active ingredient that acts directly at the root of the pimple, to make it disappear on the surface, permanently. ​

Discover the secrets of our hero anti-blemish treatment.

Cleanance: the skincare range to fight pimples

The skincare and hygiene range recommended by dermatologists reduces excess sebum, blemishes and blackheads effectively and durably.


A treatment designed with dermatologists

  • Reduces pimples and blackheads from 7 days¹
  • Limits the recurrence of new imperfections

Our anti-blemish concentrate was co-developed with Pr Saurat, an internationally renowned dermatologist and acne specialist. Today, our treatment is prescribed by dermatologists all over the world2 .


ComedoclastinTM: acts at the root of the pimple

A pimple on the face is a micro-comedone in the deeper layers of the skin. As long as it is not eliminated in-depth, the imperfection returns. This is the reason why you wonder why your pimples persist even into adulthood. ​


The Cleanance Comedomed treatment contains ComedoclastinTM. This plant extract, derived from milk thistle seeds, acts on the invisible part of the pimple (micro-comedone) and thus makes it disappear permanently on the surface.

Healthy skin from 1 week and for 1 year

The Cleanance Comedomed anti-blemish concentrate is the subject of extensive clinical studies. 

Results over 1 year of study: reduced pimples from 7 days 1  and no recurrence for 90% of users 3 .


Cleanance Comedomed: the expert ally for acne-prone adult skin.

7 days

for visible and lasting results1


Anti-recurrence action³


Reduces blemishes by -45% from 2 months⁴


Cleanance Comedomed

Localized Drying Emulsion

  • Localized and rapid drying action
  • Limits residual marks

Cleanance Comedomed Localized drying care is a one-off "SOS" treatment to dry and absorb localized imperfections while limiting residual marks. Visible efficacy from 1 day of application *.


Easy to dose and apply thanks to its targeted cannula tip, this featherweight emulsion penetrates quickly.


Cleanance Cleansing Gel

  • New formula to gently purify the skin
  • Long-lasting elimination of sebum, shine and impurities

The facial cleansing phase: this is the basis of care for skin with imperfections! Cleanance Cleansing gel helps to purify and mattify the skin without attacking it. It gently removes the impurities that contribute to clogging the pores (dust, pollution particles, make-up) and reduces the excess sebum at the origin of pimples for clean, fresh skin.


Discover all our solutions for oily skin with imperfections

CLEANANCE micellar water

No-rinse, it gently cleanses, mattifies and removes impurities and make-up from the face and eyes of combination to oily, blemish-prone skin.

Cleanance women night cream

Targeted clarifying cream for problematic adult, blemish-prone skin helps reduce the appearance of blemishes, spots and residual marks and improves the appearance of fine lines for a smooth, soft and youthful complexion.


Cleanance spf50+ sunscreen

Cleanance Sun SPF 50+ offers ultra-broad spectrum sun protection. This sun cream is ideal for protecting oily skin with imperfections on a daily basis. With Monolaurin, a sebo-reducing active ingredient, it visibly reduces blemishes and helps prevent the appearance of marks due to sun exposure. Cleanance Sun 50+ leaves an imperceptible, non-shiny finish on the skin when applied and is an excellent base for everyday make-up. The formula is also water resistant.

Cleanance mattifying emulsion

Long-lasting, hydrating and mattifying skincare for oily and shiny skin. Visibly reduces excess sebum.

Cleanance hydra

Rich, nourishing cream helps minimize the appearance of redness while boosting the skin's natural defences that have been compromised from harsh, drying acne treatments. Ideal for use in conjunction with acne treatments.


Under an anti-acne treatment, my skin is particularly dry, so I opted for Cleanance HYDRA. This cream moisturizes the skin well and leaves a non-greasy feeling, it penetrates the epidermis deeply, I recommend it morning and evening for people under treatment!



At the heart of our range


Limits the transformation of sebaceous follicles into micro-comedones.

Avène Thermal Spring Water

Restores with all its soothing and anti-irritant properties.

Dermatological innovation


A new comedolytic active ingredient of vegetable origin: COMEDOCLASTIN ™


Innovation with patented properties *, exclusively developed by Pierre Fabre Laboratories, Comedoclastin ™ is made from milk thistle seeds. 


This unique active ingredient provides an unprecedented response in the management of mild to moderate acne. It reduces pimples and limits their reappearance by acting at a key stage in the process of formation of blemishes, from the root. By preventing the sebaceous follicles from turning into micro-comedones, it helps to resist pimples.


To reconnect you with your skin

Teens, young adults, parents of teens: you are not alone when it comes to acne. Pimples shouldn't be a cause for concern regardless of your age. More than ever, Avène Dermatological Laboratories support you. 


“The gift of appeasing”, our brand signature, is the mantra that guides our Laboratory in all its research and its perpetual quest for innovation. Thus, we have been able to develop our skincare offer to become today the only dermo-cosmetic range for oily skin with imperfections that fully and specifically responds to all stages of acne. 


And as we are fully aware of the psychological repercussions they can induce, we are also here to treat their scars invisible to the naked eye.


To help you live more serenely, we share with you some daily tips that apply to all ages and that can change everything!

Tip # 1

After finding the right products for your skin, the most important thing is to apply them daily. Re-gu-la-ri-té is synonymous with efficiency! Apply your treatment every day after cleansing your skin. 


When it comes to efficiency, it rhymes with simplicity! Do not multiply the products. Stick to a simple routine and the result will be better. 

Tip # 2

Applying makeup when you have pimples is possible as long as you use non-comedogenic makeup and remove makeup EVERY NIGHT! 

A little beauty has several advantages: first, you have the opportunity to hide your imperfections for more serenity. Then, when you are made up, you are much less likely to touch your spots! 

Tip # 3

This is not a secret. To feel better about yourself, it is important to gain serenity. Sport is a great ally!


The practice of a sport improves health, allows better sleep, helps to evacuate toxins and reduces stress. All of these good things contribute to better skin quality!


Do you have a doubt or maybe a question? We are always here for you

Does acne eventually go away on its own?

This is sometimes true, especially in the case of hormonal acne in adolescence. On the other hand, it is possible that acne lasts until adulthood. Women are mainly concerned. Hormonal variations (especially pregnancy) are factors that trigger acne breakouts, not to mention UV rays, dust and air pollution - likely to be factors influencing acne. We must react quickly and not hesitate to consult a health professional for good advice.

Acne scars, what can be done?

When it comes to acne scars, prevention is better than cure, getting rid of them is long and expensive, laser treatments, chemical peels, microdermabrasion ...


The best option is therefore to have a well-adapted and effective anti-blemish routine. The fewer pimples there are, the less scars there will be! Fortunately, there are double-action skincare products that reduce pimples, reduce hyperpigmentation of scars and reduce light scars such as Cleanance WOMEN Smoothing Night Care.

Maskne, how to fight against this form of acne linked to the mask?

Wearing a mask can "suffocate" the skin, which can therefore be more sensitive to breakouts.

Our advice: Hygiene is essential, morning and evening. Boost skin hydration but with products for oily or acne-prone skin that will hydrate by reducing blemishes and limiting their reappearance. And take care to wear a clean mask daily because it can become saturated with cosmetics and creams which will make it more irritating and comedogenic. Fortunately, there are double-action treatments that reduce pimples, reduce hyperpigmentation of scars and reduce light scars. such as WOMEN Cleanance Smoothing Night Care.


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1 Tolerance and efficacy study under dermatological control on 51 subjects, use of Cleanance Comedomed twice a day for 56 days. 2 Data on file in over 90 countries, 2021. 3International observational clinical study, 90% of patients without acne relapse at T6 months, (according to the definition of relapse in the GEA ≥3 protocol requiring the introduction of oral or local drug treatment), 48 subjects, 2 applications per day of Cleanance Comedomed alone for 6 months. 4 36 subjects with slight to moderate blemishes. Comparative clinical study (group treated twice / day N = 18), control group (N = 18) for 56 days.
*Patent pending