Act on the root causes of skin ageing by stimulating cellular regeneration.


In 2022, Eau Thermale Avène Dermatological Laboratories is innovating with an approach that revolutionises anti-ageing: acting directly on the causes of ageing.

The new Hyaluron Active B3 range acts on the cause of ageing, thanks to a combination of 2 longevity boosting active ingredients: niacinamide and hyaluronic acid.


To act at the source of skin ageing and boost cell regeneration.

Hyaluron Active B3 Cell Renewal Cream

  • Rich in Hyaluronic Acid and Niacinamide
  • Smoothes and corrects wrinkles 
  • Excellent makeup base 


Comfortable and velvety, this treatment instantly smoothes and gives radiance to the skin. Thanks to its Niacinamide content, it acts on the root cause of skin ageing and prolongs the life of cells*.

Innovation is also found in eco-design: its glass jar is recyclable. 
*in vitro test using Niacinamide


My skincare, my hero!


Firmer skin¹


Naturally derived ingredients

15 days

to regenerate the skin²

Hyaluron Activ B3 Multi-intensive Night Cream

  • Rich in Retinal (10x more active than Retinol)
  • Activates collagen synthesis
  • Firms and regenerates the skin in depth


This is the night treatment you need. A true cocooning treatment for the night, its delicately scented texture brings comfort to the skin. From 15 days, it is repaired, firmer and wrinkles are filled*

*% satisfaction, 70 users.


"This cream is a real radiance booster for my skin! Its velvety texture is very pleasant and above all non-sticky and the smoothing effect is visible upon application. I use it after the plumping serum and my skin stays comfortable all day. My skin tolerates it perfectly, which is rare for an effective anti-ageing treatment."


Hyaluron Activ B3 Triple Correction Eye Cream

  • Corrects wrinkles and fine lines
  • Decongests the eye contour
  • Revives the radiance of the eyes


Eye treatment containing dextran sulfate, pure hyaluronic acid and niacinamide to act on the cause of aging.* The eye contour is firmer. Wrinkles, bags, dark circles are filled. 

*in vitro test, using niacinamide.


At the heart of our range

Mid-size hyaluronic acid

It's small size allows it to penetrate the skin to recharge it with natural hyaluronic acid and thus firm it, plump it and fill in wrinkles. 


Also known as vitamin B3, it acts on the cause of ageing. Reduces the appearance of wrinkles and age spots, and improves skin elasticity. 


Do you have a doubt, or a question? We are always here for you.

At what age should you start using Hyaluron Activ B3 treatments?Hyaluron Activ B3 treatments are formulated for women showing signs of skin ageing. They act on the cause of ageing by boosting cell regeneration in order to correct wrinkles and boost the firmness and radiance of the skin. If you notice these signs on your face, Hyaluron Activ B3 treatments are made for you.

I have sensitive skin prone to allergies, can I use Hyaluron Activ B3 treatments containing Retinal?Hyaluron Activ B3 products have been developed to minimize the risk of allergic reactions. However, if allergies or intolerances are very severe, it is advisable to turn to the Tolérance ranges or creams for intolerant skin. Either way, we recommend that you seek advice from your dermatologist.

I have combination skin, can Hyaluron Activ B3 Multi-Intensive Night Cream suit me?As the texture of the HYALURON ACTIV B3 Multi-Intensive Night Cream is non-greasy and non-comedogenic, this Cream is suitable for all skin types.


  • North
  • Central
  • South Eastern
  • South
  • Gozo

Contact us to help you choose the best dry and/ or atopic skin care products

Follow us on Facebook and Instagram to keep up to date with our latest products and skin care knowledge.

1 Instrumental measurements at 2 months following the application of the Hyaluron Activ B3 Cell Regeneration Cream on 41 consumers
2 Results perceived in self-assessment on 65 users following the application of the 
Hyaluron Activ B3 Cell Regeneration Cream 1 application/day.